Electroconvulsive Therapy (ECT)
It seems quite barbaric in this day and age, but in the experience and
judgment of many physicians (and patients with severe depressions who
have received ECT and other antidepressant treatments),
electroconvulsive or “shock” therapy is the single most
effective treatment for severe depression and has a number of advantages over other treatments.
ECT works rapidly so that patients can quickly return to
productive living. It has a higher success rate for severe
depression than any other single treatment approach.
ECT is the treatment of choice when a depressed person is making
dangerous suicide attempts, because attempts are exceedingly rare after
a course of treatment has started.
In psychotic depression
where a person has lost contact with reality and has delusions and/or
hallucinations, ECT is actually more effective than most antidepressant
medications (an exception may be amoxapine (Asendin), which has been
shown to be useful for psychotic depression).
Depressed patients who are also severely medically ill usually tolerate ECT
very well and with fewer complications than when treated with
antidepressant drugs. Contrary to the common fears and dramatic
misconceptions often associated with the term “shock
treatment”, the actual physiological stress and risk from the
minimal electrical stimulus employed are very low. ECT is administered
after the patient is put to sleep with a short acting anesthetic and
after the patient’s muscles are relaxed, so that muscle
contractions from the treatment will not damage muscles or bones.
Patients do not remember or feel the treatment.
After most treatments, there is a brief period of confusion and memory
loss for recent events. This usually lasts from 20 to 60
minutes. Temporary memory loss increases with the number and
frequency of treatments but can be lessened by increasing the interval
between treatments and by “unilateral” or one sided
treatment. A new technique called brief-pulse ECT uses the
minimum amount of electricity needed to produce an effective treatment
and substantially reduces memory loss after each treatment and over a
course of treatments.
Contrary to scare stories and subjective reports of lasting memory loss,
repeated studies have failed to find any permanent effect on
memory. In fact, memory is sometimes improved after ECT, probably
because depression itself can have an adverse effect on memory.
After the usual series of 6 to 12 treatments at intervals of 2 to 3
days, some decreasing memory loss may persist for as long as several
months. Occasionally, patients complain of more persistent memory
impairment, which may not be apparent when tested objectively.
Whether this is a reflection of insensitive testing procedures and
whether this is truly a consequence of ECT continues to be
investigated. Once patients are given information about the great
effectiveness and safety of ECT, they may prefer ECT to alternative
treatments.